U.S. Markets for Interventional Cardiology Products

According to the American Heart Association, every 25 seconds someone in the United States (U.S.) will suffer a coronary event, and every 60 seconds someone will die from such an event. In the next decade, the number of people living in the U.S. who have heart conditions is expected to continue to increase along with expansion in the elderly segment of the population and growth in the number of people with chronic disorders such as cardiovascular disease, diabetes, and obesity. Currently, nearly 18 million adults age 20 or older in the U.S. suffer from coronary heart disease (CHD), which is the single largest cause of death in the U.S. and also is the greatest cause of premature and permanent disability in the labor force; CHD is responsible for more than 50% of all cardiovascular events in men and women younger than age 75, and for 1 out of every 6 deaths.

Diseases/disorders of the heart are managed using a variety of methods including noninvasive imaging, open surgery, and catheter-based modalities. Interventional cardiology is a continually evolving area of medicine that involves the use of catheter-based, or transcatheter, tools and techniques to diagnose and treat coronary vascular and structural disorders. In 2008, diagnostic and therapeutic interventional cardiology methods were employed in approximately 6,531,700 procedures in the U.S., generating an estimated $4,672.1 million in corresponding products sales, of which 89.5% was attributable to therapeutic systems sales. Diagnostic interventional cardiology products covered by the scope of this report include coronary angiography devices, intracardiac echocardiography (ICE) and intravascular ultrasound (IVUS) catheters, and physiologic intravascular stenosis assessment guidewires. Therapeutic interventional cardiology products discussed in this report include atherectomy and chronic total occlusion (CTO) crossing devices, and coronary stents as well as devices for drug-eluting balloon (DEB) angioplasty, percutaneous transluminal coronary angioplasty (PTCA), thrombectomy, transcatheter septal defect repair, and vascular access site closure.