Report Detail
U.S. Markets for Percutaneous Transluminal Coronary Angioplasty and Coronary Stent Products
Beginning with the introduction of open-heart coronary artery bypass graft (CABG) surgery in the mid-1960s, significant progress has been made in the management of coronary artery disease (CAD) including the development of less invasive catheter-based
treatment techniques, and the creation of a wide range of drugs to treat individuals with acute conditions and those who are at risk for life-threatening conditions. Despite these advancements, however, CAD remains the cardiovascular disease (CVD) with the highest mortality, causing 459,841 deaths in the United States (U.S.) in 1998.
Approximately 84% of all deaths from CVD occur in individuals over the age of 65, and according to data from the U.S. Census Bureau, the number of people in the country over the age of 60 will increase by 22% between the years 2000 and 2010. Currently, more than 12.4 million individuals in the U.S. have some form of CAD that requires ongoing management. As the American population ages, and more individuals enter the high-risk age group for CAD (i.e., men age 45 and older, and women age 55 and older), the need for CAD management services and associated products used to diagnose, monitor, and treat the disease will continue to grow. Addressing the management of CAD in an aging population requires greater efforts in early disease detection and prevention, timely and effective treatment of acute events, and aggressive management of individuals who have previously suffered an acute coronary event.
The major types of CAD—as defined in the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM)—include both chronic and acute diseases, and are defined within the general classification of ischemic heart disease.
The types of ischemic heart disease include acute myocardial infarction (MI), other acute and subacute forms of ischemic heart disease, old MI, angina pectoris, and other forms of chronic ischemic heart disease. In the absence of treatment, individuals typically advance through the various types of CAD, starting with atherosclerosis which, as it progresses, results in clinically significant ischemia of heart tissues; this leads to angina pectoris, which finally progresses to MI with frank ischemia and cardiac muscle cell death.